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AGING GRACEFULLY PART.2: Health benefits of nicotinamide adenine dinucleotide (NAD+) FOR YOUR BELOVED PETS!

4/16/2024

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Introduction to Nicotinamide Adenine Dinucleotide (NAD+)

​As pet owners, we all want our furry companions to live long, happy, and healthy lives. But as our pets age, they may start experiencing various health problems.
​
One key factor in the aging process is a decline in cellular energy production. This is where Nicotinamide Adenine Dinucleotide (NAD+) comes into play. NAD+ is a coenzyme found in every living cell and is crucial for energy metabolism.

In this article, we will explore the role of NAD+ in cellular energy production and its potential benefits for older pets.

The Role of NAD+ in Cellular Energy Productio

NAD+ plays a vital role in cellular energy production by acting as a cofactor in several metabolic reactions, such as glycolysis and oxidative phosphorylation. These processes are responsible for converting the food our pets eat into energy that their cells can use.
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As our pets age, the levels of NAD+ in their bodies decline, leading to decreased energy production and potentially contributing to the onset of age-related health issues

Understanding the Aging Process in Pets

Just like humans, pets undergo the aging process. As they grow older, their bodies undergo various physiological changes. These changes can include a decrease in muscle mass, a decline in organ function, and a decrease in the efficiency of their immune systems.
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Additionally, aging pets may experience joint problems, such as arthritis, and an increased susceptibility to diseases. By understanding the aging process, we can better address the specific health needs of our older pets. 

Common Health Problems in Older Cats and Dogs

Older cats and dogs are prone to certain health problems. 
In cats, arthritis and renal failure are common issues. It can significantly impact their quality of life. 

Dogs, on the other hand, may experience various age-related health problems, including arthritis, cognitive decline, and reduced immune function. These health issues can be distressing for both pets and their owners. 
​
Fortunately, NAD+ supplementation may offer some relief.

Benefits of NAD+ for Older Pets Managing Pain and Arthritis in Senior Dogs with NAD+

Arthritis is a prevalent condition in senior dogs, affecting their joints and causing discomfort. NAD+ has been shown to have anti-inflammatory properties, making it a potential natural option for managing pain and inflammation associated with arthritis.
​
By increasing NAD+ levels in their bodies, we can potentially reduce the symptoms of arthritis in senior dogs, improving their mobility and overall quality of life. 

Improving Joint Health in Senior Cats with NAD+

Arthritis is also a common problem in senior cats. The loss of cartilage in their joints can lead to pain and stiffness. Fortunately, NAD+ may help improve joint health in senior cats.
​
By increasing NAD+ levels, we can potentially reduce inflammation, support cartilage regeneration, and alleviate the discomfort associated with arthritis. This can greatly enhance the mobility and overall well-being of our senior feline companions. 

Choosing the Best NAD+ Supplements for Pets

Several substances, known as precursors, have the potential to elevate NAD+ levels in the body. These precursors are obtainable through supplements or dietary sources. The following are some of the precursors that can increase NAD+ levels:
  • Tryptophan
  • Nicotinic acid (also referred to as niacin or vitamin B3)
  • Niacinamide (an alternative form of vitamin B3)
  • Nicotinamide mononucleotide (NMN), which the Food and Drug Administration (FDA) has classified as an investigational drug rather than a supplement
  • Nicotinamide riboside (NR)

​When considering NAD+ supplementation for our older pets, it is essential to choose the right supplements. Look for reputable brands that offer high-quality products specifically formulated for pets.
Consider supplements that contain other beneficial ingredients, such as antioxidants and joint-supporting compounds. It's also a good idea to consult with your veterinarian to ensure that the supplement is appropriate for your pet's specific needs and health condition. 

Natural Foods that Increase NAD+ for Pets

​In addition to supplements, certain natural foods can help increase NAD+ levels in pets.
Foods rich in Tryptophan and niacin, such as beef and fish, can provide precursors for NAD+ synthesis. Other foods, like broccoli, cabbage, avocado, and mushrooms, contain compounds that support NAD+ production. Including these foods in your pet's diet can be a natural and delicious way to boost their NAD+ levels and support their overall health. 

Potential Risks of Increasing NAD+ Level

When it comes to boosting NAD+ levels in older pets through diet changes and supplements, it's important to be cautious. There are some risks to be aware of. These include:
  • Liver toxicity
  • Tumor development
  • Itching
  • Nausea
  • Low platelet count
  • Potential interactions with medications
Because NAD+ is relatively new in the pet health field, there isn't a lot of long-term safety data available yet.
​
Just like with any changes to your pet's diet, it's crucial to introduce new supplements gradually and keep a close eye on how your pet responds. Some pets might have allergies or sensitivities, so it's important to watch out for any negative reactions.
It's generally safer to focus on getting NAD+ precursors from a balanced, natural food diet rather than using high-dose supplements. This approach can help minimize the potential risks associated with NAD+ elevation in older pets.
Additionally, it's always a good idea to consult with your veterinarian before making any significant changes to your pet's diet.

Conclusion

​The Potential of NAD+ for Improving the Health of Older Pets As our pets age, they may experience a decline in cellular energy production, leading to various health problems.
Nicotinamide Adenine Dinucleotide (NAD+) plays a crucial role in cellular energy metabolism and can potentially alleviate age-related issues in older pets. By managing pain and arthritis in senior dogs, improving joint health in senior cats, and incorporating NAD+-boosting foods and supplements into their diets, we can enhance the well-being and quality of life of our aging furry companions.
If you're interested in exploring the benefits of NAD+ for your older pet, contact me to schedule an appointment and discuss the best options for your furry friend's specific needs.

Need Help?

​Interested in incorporating natural sources of NAD+ into their diet or exploring NAD+ supplements specifically formulated for pets? ​If you feel your pet could benefit from natural food and herbal care including mushrooms, consider scheduling an appointment with me. I’m happy to help you and your furry friend!
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Resources:
https://www.verywellhealth.com/nad-supplements-7966461
https://link.springer.com/article/10.1007/s13668-023-00475-y
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30495-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413116304958%3Fshowall%3Dtrue
https://pubmed.ncbi.nlm.nih.gov/24014409/
https://www.mdpi.com/2072-6651/13/1/50
https://www.sciencedirect.com/science/article/abs/pii/S0531556519307582?via%3Dihub
https://ard.bmj.com/content/82/Suppl_1/836.
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    Yuki Konno MS, LVT, CVWHM(civt)

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